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Global COVID cases rise a bit; Delta variant in nearly 100 nations

After falling for 8 weeks in a row, the world’s weekly number of COVID cases increased slightly last week, as multiple countries battle surges, including those in Africa, the World Health Organization (WHO) said yesterday in its latest situation report. As case decline stalls, deaths continue to drop The case rise was slight, at 2.72%. […]

COVID-19 Scan for Jun 29, 2021

Analysis of 10 studies shows ivermectin not effective in treating COVID-19 A new meta-analysis of 10 studies shows ivermectin (IVM), an anti-parasite drug, is not an effective treatment for COVID-19 and is not a viable treatment option for patients. The study was published yesterday in Clinical Infectious Diseases. The authors analyzed results from 10 randomized […]

COVID cuts US life expectancy, with minorities hit hardest

The COVID-19 pandemic’s effect on US life expectancy has disproportionately hit minorities, according to new studies in BMJ and JAMA Network Open, with the former finding that overall US life expectancy—which dropped almost 2 years from 2018 to 2020—hasn’t been this low since 1943, during World War II. “I’ve been studying the US health disadvantage […]

Nearly all US COVID-19 deaths now preventable

For the first time since the COVID-19 pandemic began in earnest in March of 2020 in the United States, nearly all of the deaths recorded in recent weeks were preventable, occurring in unvaccinated Americans. According to an Associated Press analysis of Centers for Disease Control and Prevention (CDC) data from May, only about 150 of […]

Stewardship / Resistance Scan for Jun 25, 2021

New C difficile guidelines favor fidaxomicin over vancomycin Guidelines published yesterday by the Infectious Diseases Society of America (IDSA) and the Society for Healthcare Epidemiology of America (SHEA) contain three new recommendations for treating adults who have Clostridioides difficile infection (CDI). For both initial and recurring CDI cases, the new guidelines, published in Clinical Infectious […]

COVID-19 Scan for Jun 24, 2021

COVID-19 vaccination tied to reduced household transmission COVID-19 transmission among household members may be reduced 40% to 50% when a person has been vaccinated 21 days or more, according to a New England Journal of Medicine letter to the editor yesterday. The researchers looked at more than 1 million household contacts in England from Jan […]

Diagnosis and Management of Coagulation Disorders Related to COVID-19

Although the clinical features of SARS-CoV-2 infection were first reported in 2019, it has also been established that hospitalized patients with COVID-19, especially those admitted to intensive care unit (ICU), have an increased risk for venous thromboembolism (VTE) despite prophylactic dose anticoagulation.1-4 As a result, some experts have suggested that higher anticoagulation targets may be […]

‘Stolen moments’: Families anguish over separation from dying COVID patients

In-depth interviews with 19 adult family members of patients lost to COVID-19 during the first pandemic wave in France uncover difficulties forging a bond with intensive care unit (ICU) staff, being separated from their loved ones at the time of greatest need, and grief over “stolen moments.” Led by researchers at Saint Louis University Hospital […]

US COVID-19 cases continue to fall—as do vaccinations

The daily number of new COVID-19 cases continues to drop across the country, to tallies not seen since 15 months ago, when the pandemic began. But new Centers for Disease Control and Prevention (CDC) data show that young adult vaccine uptake is below that of older adults. The United States reported 3,892 new COVID-19 cases […]

ASP Scan (Weekly) for Jun 18, 2021

Our weekly wrap-up of antimicrobial stewardship & antimicrobial resistance scans Outpatient antibiotic durations frequently longer than needed, study finds Nearly 40% of outpatient antibiotic prescriptions in an integrated healthcare system in Denver were longer than necessary, researchers reported yesterday in Open Forum Infectious Diseases. The analysis of antibiotic prescribing across the ambulatory care network of Denver […]